Influence of the Biological Medium on the Properties of Magnesium Doped Hydroxyapatite Composite Coatings

In this paper, the stability of magnesium-doped hydroxyapatite/chitosan (MHC) suspension obtained with sol-gel approach was evaluated using nondestructive ultrasound measurements. The MHC coatings by spin-coating technique were characterized before and after immersion for 7 14 days, respectively, in Dulbecco’s modified eagle medium (DMEM) scanning electron microscopy, equipped an EDAX detector. Also, functional groups present on surface analyzed aid attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy. microstructure two commentary techniques, namely atomic force microscopy (AFM) metallographic (MM). influence DMEM biological properties studied vitro studies primary osteoblast HCT-8 cell lines. Our results revealed that both morphology chemical composition allow rapid development a new apatite layer their DMEM. Preliminary underlined noncytotoxic effect samples proliferation lines, which makes them promising candidate applications fields such as orthopedics or dentistry. antifungal assay assessed Candida albicans ATCC 10231 showed good inhibitory effect. made basis composite could contribute to increasing degree success implants decreasing risk infections postoperative inflammation.